Synergistic effect between eNOS gene G894T and GNB3 gene C825T polymorphisms in patients with essential hypertension
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چکیده
منابع مشابه
Prevalence of GNB3 C825T Gene Polymorphism in Children with Vesicoureteral Reflux in Kerman
Background & Aims: Vesicoureteral Reflux (VUR) is a congenital defect of the urinary tract which has been reported in approximately 1% of children. Several immunological and genetic factors are listed as major causes of this problem. The C825T polymorphism of the GNB3 gene is among the genetic factors that may be involved in the development or progression of the disease. Participatory role o...
متن کاملAssociation of eNOS gene polymorphisms T-786C and G894T with blood pressure variability in man.
The aim of this study was to evaluate the association of single nucleotide polymorphisms (SNPs) T-786C and G894T in the gene encoding eNOS with blood pressure variability (BPV) in man. Blood pressure was recorded beat-to-beat at rest three times in periods of one week (5 min, Finapres, breathing at 0.33 Hz) in 152 subjects (19-24 years). Systolic (SBPV(0.1r)/SBPV(0.1a)) and diastolic (DBPV(0.1r...
متن کاملAssociation of eNOS Gene Polymorphisms G894T and T-786C with Risk of Hepatorenal Syndrome
Background. There are no studies investigating the relationship between endothelial nitric oxide synthase (eNOS) gene polymorphisms and hepatorenal syndrome (HRS). Aim. The purpose of this study is to elucidate whether eNOS gene polymorphisms (G894T and T-786C) play a role in the development of type-2 HRS. Methods. This study was carried out in a group of 92 patients with cirrhosis (44 patients...
متن کاملAssociation of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China.
Endothelial nitric oxide synthase (eNOS) plays an important role in maintaining blood pressure homeostasis and vascular integrity. Polymorphisms in the eNOS gene have been found to be associated with hypertension in different human populations, including Northern and Southern Chinese Han populations. To examine the relationship of three eNOS gene polymorphisms, T-786C (rs2070744), G894T (...
متن کاملPrediction of the Risk for Essential Hypertension among Carriers of C825T Genetic Polymorphism of G Protein β3 (GNB3) Gene
BACKGROUND The guanine nucleotide-binding protein beta polypeptide 3 (GNB3) 825T allele encodes a product that enhances the activation of heterotrimeric G proteins, which is associated with the occurrence of the splice variant Gβ3 s that could play a role in vascular reactivity and hyperproliferation of smooth muscle cells, that makes such proteins attractive candidate gene products for suscept...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2005
ISSN: 0895-7061
DOI: 10.1016/j.amjhyper.2005.03.450